About Us

John Laragh and Jean Sealey developed The Laragh Method, a personalized drug selection system of treating hypertension based on plasma renin (PRA) testing.

John H. Laragh MD

Physician scientist who discovered that plasma renin and sodium interact to support normal blood pressure, and that excesses in plasma renin or sodium interact to cause hypertension.

Jean E. Sealey D.Sc.

Clinical scientist who developed the PRA test and described how to apply it in the Laragh Method.