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    • John H. Laragh MD >
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      • Aldosterone and hypertension
      • RAAS, hypertension and cardiovascular complications
      • Volume-vasoconstriction hypothesis of blood pressure controlage
      • The RAAS in health & CV disease
      • RAS Blockers: ACEIs and ARBs and renin blockers
      • Plasma renin guided treatment of hypertension
      • 1954-1960
      • 1966-1970
      • 1951-1965
      • 1971-1975
      • 1976-1980
      • 1981-1985
      • 1986-1990
      • 1991-1995
      • 1996-2000
      • 2001-2015
    • Jean E. Sealey D.Sc. >
      • 1965-1970
      • 1970-1975
      • 1976-1980
      • 1981-1985
      • 1986-1990
      • 1991-1995
      • 1996-2000
      • 2001-2017
  • PRA HTN App
  laragh method: Plasma renin guided therapy for high blood pressure
  • Home
  • Treatment Guidelines
    • Untreated HTN
    • Unsuccessfully Treated HTN
    • Anti-V & R drug types
  • PRA Test
    • PRA
    • Direct Renin
  • Renin & Salt
    • BP = V x R
    • Hypertension video
    • Educational Videos
  • About Us
    • John H. Laragh MD >
      • Curriculum Vitae
      • Aldosterone and hypertension
      • RAAS, hypertension and cardiovascular complications
      • Volume-vasoconstriction hypothesis of blood pressure controlage
      • The RAAS in health & CV disease
      • RAS Blockers: ACEIs and ARBs and renin blockers
      • Plasma renin guided treatment of hypertension
      • 1954-1960
      • 1966-1970
      • 1951-1965
      • 1971-1975
      • 1976-1980
      • 1981-1985
      • 1986-1990
      • 1991-1995
      • 1996-2000
      • 2001-2015
    • Jean E. Sealey D.Sc. >
      • 1965-1970
      • 1970-1975
      • 1976-1980
      • 1981-1985
      • 1986-1990
      • 1991-1995
      • 1996-2000
      • 2001-2017
  • PRA HTN App
The Renin-Angiotensin-Aldosterone System (RAAS) in Physiology and Medicine
SELECTED REFERENCES - Chronological

Aldosterone and hypertension

Laragh JH, Stoerk HC: A study of the mechanism of secretion of the sodium-retaining hormone (aldosterone). Plasma K+ stimulates aldosterone secretion. J. Clin. Invest. 36:383-392, 1957.
Ulick S, Laragh JH, Lieberman S: The isolation of a urinary metabolite of aldosterone and its use to measure the rate of secretion of aldosterone by the adrenal cortex of man. Trans. Assoc. Am. Physicians 71:225-235, 1958.
Laragh JH, Ulick S, Januszewicz W, Deming WB, Kelly WG, Lieberman S: Aldosterone secretion and primary and malignant hypertension. J. Clin. Invest. 39: 1091-1106, 1960.
Laragh JH, Ulick S, Januszewicz V, Kelley WG, Lieberman S: Electrolyte metabolism and aldosterone secretion in benign and malignant hypertension. Ann. Intern. Med. 53:259-272, 1960.
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  • Home
  • Treatment Guidelines
    • Untreated HTN
    • Unsuccessfully Treated HTN
    • Anti-V & R drug types
  • PRA Test
    • PRA
    • Direct Renin
  • Renin & Salt
    • BP = V x R
    • Hypertension video
    • Educational Videos
  • About Us
    • John H. Laragh MD >
      • Curriculum Vitae
      • Aldosterone and hypertension
      • RAAS, hypertension and cardiovascular complications
      • Volume-vasoconstriction hypothesis of blood pressure controlage
      • The RAAS in health & CV disease
      • RAS Blockers: ACEIs and ARBs and renin blockers
      • Plasma renin guided treatment of hypertension
      • 1954-1960
      • 1966-1970
      • 1951-1965
      • 1971-1975
      • 1976-1980
      • 1981-1985
      • 1986-1990
      • 1991-1995
      • 1996-2000
      • 2001-2015
    • Jean E. Sealey D.Sc. >
      • 1965-1970
      • 1970-1975
      • 1976-1980
      • 1981-1985
      • 1986-1990
      • 1991-1995
      • 1996-2000
      • 2001-2017
  • PRA HTN App